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[eleven] Albrecht-Buehler has prompt this rule would be the consequence of genomes evolving by a process of inversion and transposition. This method will not seem to acquire acted around the mitochondrial genomes. Chargaff's next parity rule appears being extended within the nucleotide-amount to populations of codon triplets, in the case of full single-stranded Human genome DNA. A sort of "codon-stage second Chargaff's parity rule" is proposed as follows:
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The 2nd rule retains that both equally %A ~ %T and %G ~ %C are valid for every of the two DNA strands.[three] This describes only a world element of the base composition in only one DNA strand.
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Chargaff's 2nd rule seems to be the consequence of a more elaborate parity rule: in a single strand of DNA any oligonucleotide is present in equivalent numbers to its reverse complementary nucleotide. Due to the computational requirements this hasn't been verified in all genomes for all oligonucleotides. It's been verified for triplet oligonucleotides for a considerable details set.
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